Russellville is the county seat and largest city in Pope County, Arkansas, United States, with a 2022 estimated population of 29,133. It is hom…Russellville is the county seat and largest city in Pope County, Arkansas, United States, with a 2022 estimated population of 29,133. It is home to Arkansas Tech University. Arkansas Nuclear One, Arkansas' only nuclear power plant is nearby. Russellville borders Lake Dardanelle and the Arkansas River.