In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins. A ...

demonstrating the proficiency of MZ1 to position the target protein for degradation and the favorability of the target protein for ubiquitination by UBE2R1. The importance of degraders for ...

The Centre for Targeted Protein Degradation (CeTPD) at the University of Dundee is one of the world's leading centers for ...

In a study published in PNAS, a research team developed a new reinforcement learning-based enhanced sampling method called ...

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These chambers are linked by narrow channels, requiring a protein ... exposed by transient local unfolding events. A prediction of this model is that the local structure near the degradation ...

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RIVERSIDE, Calif. -- In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing ...