Transport proteins are responsible for the ongoing movement of substrates into and out of a biological cell. However, it is ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune ...

The researchers discovered that modulation of a specific molecular cascade, the mTOR signaling pathway, in these stem cell models induces a dormant state remarkably akin to diapause. "The mTOR pathway ...

Two new papers by a team of researchers at Boston University, the Indiana University School of Medicine and the Alzheimer’s Disease Neuroimaging Initiative (ADNI), and the German Center for ...

FAO is catalyzed by the mitochondrial trifunctional protein (MTP) and, if overloaded, generates ROS. ROS are boosted during ...

The inhibition of ERK5 is a potential complementary strategy for countering FAK inhibitor resistance in patients with lung ...

Metabolic pathways are enzyme-mediated biochemical reactions that lead to biosynthesis (anabolism) or breakdown (catabolism) of natural product small molecules within a cell or tissue. The ...

In glaucoma, the disturbed pathways involve lipid metabolism and the carnitine shuttle pathway, with increased and decreased ...

This review uniquely explores the intricate crosstalk between apoptosis, necroptosis, and other cell death pathways, discussing their roles and interactions in the pathogenesis of cardiac involvement ...

A recent study published in Nutrients explores the causal associations between insomnia and metabolic pathways in the gut microbiome. Up to 30% of the global population has insomnia, particularly ...

Glutamine synthetase knockout Chinese Hamster Ovary (GS-CHO) cells are one of the leading mammalian cell lines used to produce monoclonal antibodies (mAbs) and other recombinant therapeutic proteins, ...