This protein is fundamental for managing iron levels ... all of which can significantly impact daily functioning and quality ...

The team developed a high-throughput imaging platform to assess the influence of nearly 3,500 mutations on protein location. They found that roughly one in six disease-causing mutations led to ...

Improving our understanding of the impact of mutations on protein localization is essential to elucidating the critical role of this malfunction in a wide range of human diseases. The research ...

Their hope is that understanding the impact of pathogenic mutations on the protein interactome could help shorten the time required for drug development and clinical trials. “In theory ...

Scientists have designed a publicly-available software and web database to break down barriers to identifying key protein-protein interactions to treat with medication. The computational tool is ...