This study presents a valuable finding on the molecular mechanisms that govern GABAergic inhibitory synapse function. The authors propose that Endophilin A1 serves as a novel regulator of GABAergic ...

Over the last few years, the SARS-CoV-2 virus, responsible for COVID-19, has undergone significant changes, evolving from the ...

Cocrystal Pharma ( (COCP) ) has issued an announcement. Cocrystal Pharma, Inc. is leveraging its innovative, structure-based drug discovery ...

Department of Medicinal Chemistry, Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, Piscataway, New Jersey 08854, United States Center for Advanced Biotechnology and ...

CRF: Circulating recombinant form; NNRTI: Non-nucleoside reverse-transcriptase inhibitor; NRTI: Nucleos(t)ide analog reverse-transcriptase inhibitor. Eight nucleos(t)ide analog reverse ...

Also known as selective COX-2 inhibitors, these medications treat inflammatory pain. Selective COX-2 inhibitors are a type of nonsteroidal anti-inflammatory medication (also known as NSAIDs).

Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB T6G 2R3, Canada Li Ka Shing Institute of Virology, University of Alberta, Edmonton, AB T6G 2E1, Canada Department ...

ACE inhibitors are best known for treating high blood pressure. They work by targeting the hormone angiotensin II. Angiotensin-converting enzymes (ACE) inhibitors help blood vessels to relax and open.

This important study explores the interplay between gene dosage and gene mutations in the evolution of antibiotic resistance. The authors provide solid evidence to connect proteostasis with gene ...