Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

The Chicago White Sox lost again on Friday night, this time to the San Diego Padres. The 3-2 loss in 10 innings came after the White Sox tied the game with two ...

Dylan Cease has yet to complete his first season with the Padres. But, that has not stopped him from becoming an icon in San Diego. The 28-year-old is featured ...

In a thrilling finish at Petco Park, the San Diego Padres pulled off a vital 3-2 victory against the struggling Chicago White ...

The Minnesota Twins’ decision to stand pat at the trade deadline, despite glaring bullpen needs, has backfired. Meanwhile, ...

The San Diego Padres (88-66) will host the Chicago White Sox (36-118), Saturday at 8:40 p.m. ET, with the White Sox on a ...

Andrew Benintendi’s Chicago White Sox face the San Diego Padres on Sept. 21 at 8:40 PM ET, and will see starter Martin Perez ...

Chicago White Sox (36-118, fifth in the AL Central) vs. San Diego Padres (88-66, second in the NL West) San Diego; Saturday, ...

Alec Bohm hit a three-run homer to cap a six-run fourth inning Friday night for the visiting Philadelphia Phillies, who ...

Fernando Tatis Jr.'s run-scoring hit leading off the 10th lifted the Padres to a 3-2 victory over the White Sox Friday.

San Diego Padres manager Mike Shildt has defended closer Robert Suarez lately but the question must be asked: Does a likely playoff-bound team with World Series dreams have a serious question to ...

Preview the Sept. 21 matchup between the San Diego Padres and Chicago White Sox with odds over/under, game spread, betting ...