Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune ...

Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have identified key ...

When an aggressive cancer launches an invasion on the human body, anything that can be done to slow down or better understand that fast-paced assault is going to be a bonus.

The researchers discovered that modulation of a specific molecular cascade, the mTOR signaling pathway, in these stem cell models induces a dormant state remarkably akin to diapause. "The mTOR pathway ...

Transport proteins are responsible for the ongoing movement of substrates into and out of a biological cell. However, it is ...

We now have all the pieces: Apple's iPhone 16 series is here, Google's Pixel 9 lineup is out, and Samsung's Galaxy S24 series still shines bright. We reviewed and tested them all to help you find ...

Sep. 25, 2024 — New research suggests that pigs may function as a transmission vehicle for a strain of the hepatitis E virus (HEV) common in rats that has recently been found to infect ...

Chromatin immunoprecipitation (ChIP-seq) is the most common approach to observe global binding of proteins to DNA in vivo. The occupancy of transcription factors (TFs) from ChIP-seq agrees well with ...

Recently, microbiota-derived tryptophan metabolism and AMPK/mTOR pathway were found to be strongly linked to ... we would further reveal the gene structure and gene expression status of individual ...

Mitigating inflammation, inhibiting immunosenescence, and eliminating senescent cells could be promising strategies for enhancing vaccine responses in older people. The mTOR signalling pathway greatly ...

TnpB is an ancestor of this well-known 'gene scissor' but is much smaller and thus easier to transport into cells. Using protein engineering ...