The Arizona Department of Transportation advises drivers to allow extra travel time or take alternative routes on closed or restricted freeways.

In addition, the westbound US 60 (Superstition Freeway) ramp to eastbound I-10 will be closed from 10 p.m. Friday to 5 a.m.

Work crews will be on the roads beginning Friday through Monday morning on multiple freeways for construction this weekend.

There will be notable restrictions and closures on Loop 101 and Interstate 10, as well as on- and off-ramp closures.

Westbound I-10 is shut down at 59th Avenue after a deadly shooting Wednesday morning. Eastbound lanes are not impacted.

All westbound lanes were shut down at 75th Avenue in west Phoenix. A large police presence was seen in the area.

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Several miles of I-80 in Mercer County was shut down due to multiple crashes Tuesday, Pennsylvania State Police said.

A crash outside the Gerber Collision and Glass in Tempe shut down the business as its employees sprung into action to help save the drivers. FOX 10's Ellen McNamara has the story.