Meanwhile, the company employed lobbying firms to “work on the need for Limulus Amebocyte Lysate (LAL) product and synthetic products to be regulated similarly in terms of safety and ...

The LAL segment manufactures endotoxin-detecting reagents made from limulus amebocyte lysate that are used to control quality in the pharmaceutical manufacturing process. Seikagaku generates the ...

All substances used in these experiments were endotoxin-free, as determined by a Limulus amebocyte lysate assay (Thermo Fisher Scientific, Waltham, MA, USA). For ex vivo NET structures generation, a ...

As part of the Marine Biological Laboratory’s Falmouth Forum series, biologist Michael Dawson will give a talk titled “The Horseshoe Crab: Ancient Mariner and Modern Medicine,” on Friday, November 22, ...

To make sure their products don’t contain endotoxins, drugmakers mostly use a reagent called limulus amoebocyte lysate (LAL), made from extracted crab blood. While labs once measured LAL ...

1| Incubate the cell lysate with 50 μl of a 50% slurry of glutathione-agarose beads and 25 μg of GST for 2 h at 4 °C with end-over-end mixing. The amount of lysate needed to detect an ...

Joint Centre of Translational Medicine, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang 325000, China Joint Centre of Translational Medicine, The First Affiliated ...