The EMBO Journal2h
Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon γ pathway
To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...
The EMBO Journal1d
A shorter splicing isoform antagonizes ZBP1 to modulate cell death and inflammatory responses
Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...
eLife1d
Mutant mice lacking alternatively spliced p53 isoforms unveil Ackr4 as a male-specific prognostic factor in Myc-driven B-cell lymphomas
Fajac et al. then allowed these mice to breed with mice that were model organisms for a cancer called B-cell lymphoma. This revealed that male offspring that lacked alternative p53 isoforms were more ...
Primates bond for their own benefit: Study underlines the decisive role that females play
Female and male primates often form close bonds, but not purely out of affection. Close relationships usually evolve when ...
Study reveals sex-specific gene expression in adipose stem cells of mice
Researchers at Karolinska Institutet and AstraZeneca have discovered that gene expression in adipose stem cells varies ...
Nested premotor circuits activity found to drive male flies' production of distinct courtship songs
While they are courting, some animals produce distinct sound patterns that clearly convey their intentions to potential mates ...
eLife4d
Pathogenic LRRK2 causes age-dependent and region-specific deficits in ciliation, innervation and viability of cholinergic neurons
Pathogenic activating point mutations in the LRRK2 kinase cause autosomal-dominant familial Parkinsońs disease (PD). In cultured cells, mutant LRRK2 causes a deficit in de novo cilia formation and ...
SouthFlorida Reporter5d
Who Is More Likely To Lose Weight On Tirzepatide And Why?
Share on PinterestScientists have found different weight loss results in people taking tirzepatide. NurPhoto/Getty Images ...
We Know So Little About Women's Health Compared to Men's. Buy Why?
Before 1993, women were rarely included in clinical trials. Today, the medical field still doesn’t know how well many drugs ...
Hosted on MSN6d
Lupus and other autoimmune diseases strike far more women than men. Now there's a clue why
Every female cell must switch off one of its X chromosome copies ... Chang’s team decided to engineer male lab mice to artificially make Xist — without silencing their only X chromosome — and see what ...