In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins. A ...

Novel method identified protein degraders that target Pin1, a protein involved in pancreatic cancer development.

Over the last few years, the SARS-CoV-2 virus, responsible for COVID-19, has undergone significant changes, evolving from the original wild-type strains to the highly transmissible Omicron variant.

The accumulation of phospholipid-degradation products that arises from these biosynthetic pathways would disrupt the architecture of the cell membrane and these products must be either eliminated ...