In drug discovery, targeted protein degradation is a method that selectively eliminates disease-causing proteins.

The Centre for Targeted Protein Degradation (CeTPD) at the University of Dundee is one of the world's leading centers for research into how protein degraders work and how they can most effectively ...

The Lon AAA+ protease (LonA ... that NTDs enable LonA to perform protein quality control to selectively degrade proteins in damaged states and suggest that substrate discrimination and selective ...

The NLRP1 inflammasome is a multiprotein complex that is a potent activator of inflammation. Mouse NLRP1B can be activated through proteolytic cleavage by the bacterial Lethal Toxin (LeTx) protease, ...