Plasmodium falciparum ATP4 (PfATP4) is a Na + efflux pump and represents an important target for antimalarial drugs with nanomolar potency. However, the structure of PfATP4 is unknown, …

Dec 17, 2024 · Browse the most-recent publications from PNAS, publishing daily across the physical, social, and biological sciences.

Liquid–liquid phase separation (LLPS) of proteins and nucleic acids (1–4) is a versatile intracellular process, which leads to the formation of biomolecular condensates (BMCs).The …

An individual’s somatic cells have essentially the same genome, but each cell type is determined by combinations of transcription factors (TFs) bound to each gene’s regulatory regions, …

Nov 8, 2024 · Drylands are vulnerable to both natural and anthropogenic perturbations (13, 18, 19).Land degradation over the past decades or centuries, resulting mainly from intensified …

Commentaries call attention to articles of particular note.. Inaugural Articles may be submitted by newly elected NAS members as a way to introduce themselves to the readers of PNAS and …

Bacteria and their viruses, bacteriophages (phages), are estimated to be the two most abundant biological groups on Earth ().Hence, phage infections of host bacterial cells are among the …

A PDF list of Editorial Board members and staff members is posted on the current issue Table of Contents; click on the [Masthead (PDF)] link in the upper right corner.

PNAS Nexus Welcomes Submissions PNAS Nexus welcomes high-quality original research from across the biological, medical, physical, social, and political sciences, and engineering and …

Apr 23, 2018 · Atmospheric carbon dioxide removal will likely play a critical role in climate change mitigation and in deep decarbonization of energy and land sectors worldwide (1, 2).A …